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Outline of Graduate School

Admission Policy
Kitasato University was founded by Dr. Shibasaburo Kitasato, a scientist who dedicated his life to demonstrating the pioneer spirit, the spirit of gratitude, the spirits of wisdom and practice, and the spirit of indomitability. We continue to uphold these spirits today as we develop leading researchers and educators in the life sciences and aim to cultivate human resources who can benefit society by providing the advanced and specialized knowledge and technology that are required of specialists. Admission to the university is based on the following policy.

Graduate School of Pharmaceutical Sciences
—Department of Pharmaceutical Sciences (Master’s Program & Doctoral Program)


Basic selection policy
The objective of the Department of Pharmaceutical Sciences is to develop researchers and educators with advanced, professional knowledge and abilities in the life science and medicinal science fields, as well as researchers and educators capable of analyzing clinical trial data and creating clinical trial programs, and researchers and educators capable of formulating strategic and global drug development plans. Therefore, as a basic policy, students are selected from among applicants who exhibit strong interest and ability to acquire diverse knowledge and problem-solving capacities in the pharmaceutical fields, and have the potential to act as future leaders in their respective field of specialization.

Division of Pharmaceutical Sciences

Division of Pharmacy

Division of Pharmaceutical Sciences

Pharmaceutical Sciences Course :
Master’s Program, Doctoral Program

This course principally aims to develop researchers and educators with advanced, professional knowledge and abilities in the life science and medicinal science fields, as well as researchers and educators capable of analyzing clinical trial data and creating clinical trial programs, and researchers and educators capable of formulating strategic and global pharmaceutical development plans.

【Major subjects】(advanced studies, seminars, advanced experiments)

  • Special Lecture on Organic and Medicinal Chemistry
  • Seminar on Organic and Medicinal Chemistry
  • Lab.Work on Organic and Medicinal Chemistry
  • Special Lecture on Information Science for Drug Discovery
  • Seminar on Information Science for Drug Discovery
  • Lab.Work on Information Science for Drug Discovery
  • Special Lecture on Pharmacology and Pharmacognosy
  • Seminar on Pharmacology and Pharmacognosy
  • Lab.Work on Pharmacology and Pharmacognosy
  • Special Lecture on Biopharmaceutics and Biomolecular Science
  • Seminar on Biopharmaceutics and Biomolecular Science
  • Lab.Work on Biopharmaceutics and Biomolecular Science
  • Special Lecture on Pharmaceutical Health Sciences
  • Seminar on Pharmaceutical Health Sciences
  • Lab.Work on Pharmaceutical Health Sciences
  • Special Lecture on Pharmaceutical Life Sciences
  • Seminar on Pharmaceutical Life Sciences
  • Lab.Work on Pharmaceutical Life Sciences
Field of SpecializationResearch Area
Medicinal Chemistry Professor:Hideaki Fujii
  1. Drug design and synthesis of drugs for opioid receptor
  2. Investigation of interaction between drugs and receptors
  3. Research and development of drugs: analgesics, therapeutic agents for drug abuse, Alzheimer’s disease, and Parkinson’s disease
  4. Development of novel photoorganic reactions
Biomolecular Science Professor:Kumiko Sakai-Kato
  1. Studies on the physiochemical properties and the disposition of innovative drugs (nanomedicine and peptides)
  2. Analytical methods of novel amino acids and peptides
  3. Studies on physiological functions of D-amino acids by the use of the model bioorganisms (C. elegans and A. thaliana)
  4. Studies on the stereospecific metabolism enzymes of amino acids
  5. Studies on the biosynthesis and the function of bacterial D-amino acids
Synthetic Natural Products Chemistry
Professor:Tohru Nagamitsu
  1. Total synthesis and structure-activity relationship studies of natural products with interesting biological activities
  2. Synthesis of novel probe molecules
  3. Development of novel synthetic methodology
Organic Chemistry for Drug Professor:Kazuishi Makino
  1. Development of organocatalysts and organometallic catalysts
  2. Development of methods for the synthesis of oligosaccharides
  3. Development of methods for the synthesis of peptides
  4. Synthesis of biologically active compounds
Biomolecular Design Professor:Mayuko Takeda-Shitaka Structural bioinformatics and drug discovery
  1. Development of computational methods for drug discovery (predicting protein-protein and protein-ligand interactions, analyzing protein structure and function, etc.)
  2. Development of computational methods for predicting protein structures from sequences (monomer structures, complex structures and hydration structures)
Pharmacognosy Professor:Yoshinori Kobayashi
  1. Quality evaluation of traditional herbal medicines
  2. Isolation / identification of the active components from traditional medicinal plants
  3. Elucidation of the action mechanism of traditional herbal medicines
  4. Chemical modification / the total synthesis of the active compounds and its derivatives
Hygienic Chemistry Professor:Hirotaka Imai Development of therapeutic drug, the prevention methods and the mechanism of the diseases caused by lipid peroxidation
  1. Analysis of the mechanism of heart disease caused by lipid peroxidation in mice
  2. Analysis of the mechanism of novel cell death caused by lipid peroxidation
  3. Identification of sensor protein of lipid peroxidation
  4. Analysis of the association between oxidative stress and fatigue
  5. Analysis of novel mechanism of cell senescence and anti-proliferation
Public Health
Professor:Masako Kiyono
Health effects of methylmercury and bioremediation of toxic metals
  1. Analyses of molecular mechanisms of anti-methylmercury responses in mammalian cells
  2. Molecular mechanisms and engineering of plant metal homeostasis
  3. Toward heavy metals bioremediation and phytoremediation
  4. Studies on molecular mechanisms of mercurial resistance in Pseudomonas K-62
Biochemistry
Professor:Mitsuru Okuwaki
Molecular mechanism of cell growth and differentiation
  1. Aberrant gene expression and cancer
  2. Signal transduction pathways and cancer
  3. Screening of drug leads for infectious diseases
Pharmacology
Professor:Mitsuo Tanabe
  1. Neuropharmacology in particular addressing chronic pain, itch and stress mechanisms with electrophysiological, neurochemical and behavioral techniques
  2. Regulatory mechanisms of protein kinases in the central nervous system and exploration of their specific inhibitors
Molecular Pharmacology Professor:Tsutomu Nakahara
  1. Molecular mechanisms of neuronal-glial-vascular interactions in the retina
  2. Development of novel therapeutic approaches for eye diseases and disorders
Microbiology
Professor:Nobuhiko Okada
  1. Molecular characterization of type III effectors in Gram-negative bacteria
  2. Molecular mechanisms of Salmonella-induced enterocolitis
  3. Role of antimicrobial proteins in bacterial gut infection
  4. Molecular approaches to study probiotic activity in lactobacilli and bifidobacteria
Microbial Chemistry Professor:Hiroshi Tomoda
  1. Discovery of drug leads from microorganisms controlling dyslipidemia, infectious diseases, cancers and intractable diseases
  2. Identification of target molecules of microbial drug leads
  3. Mechanism of action of microbial drug leads
Pharmaceutics
Professor:Tomoo Itoh
  1. Quantitative prediction of metabolic drug-drug interactions
  2. Genetic variants of drug transporters and their function
  3. Drug interactions in the absorption process via drug transporters
  4. Drug metabolism and toxicity in UGT knock-out mice
Physical Chemistry for Drug Design 
Pharmaceutical Informatics
(Informatics Education Support) Associate Professor:Yoshihiko Nishibata
Information Processing for Drug Discovery
  1. Application of Chemical Database System for Drug Discovery
  2. Development of Novel Computer-aided Drug Discovery Methods based on Chemical Features of Compounds
Social Pharmacy
(Student Learning Support)
 
Radioisotope Research Laboratory Assistant Professor:Hikaru Sakamoto
  1. Mechanisms of lipid mediator production induced by oxidative stress
  2. Effects of non-ionizing radiation on lipid metabolism
  3. Intercellular signaling pathways participated in photo-aging
  4. Functions of purine nucleotide in cutaneous immunity
Medicinal Plant Garden Associate Professor:Eiichi Kodaira 

Biostatistics Course:
Master’s Program, Doctoral Program

This course principally aims to develop researchers and educators with advanced, professional knowledge and abilities in the life science and medicinal science fields, as well as researchers and educators capable of analyzing clinical trial data and creating clinical trial programs, and researchers and educators capable of formulating strategic and global pharmaceutical development plans.

【Major subjects】(advanced studies, seminars, advanced experiments)

  • Special Lecture on Biostatistics(Ⅰ、Ⅱ、Ⅲ)
  • Seminar on Biostatistics(Ⅰ、Ⅱ)
  • Lab.Work on Biostatistics
  • Comprehensive Laboratory on Biostatistics
  • Introduction to Biostatistics
  • Special Lecture on Biostatistics
  • Seminar on Biostatistics
  • Research Work on Biostatistics
Field of SpecializationResearch Area
Biostatistics
Professor:Masahiro Takeuchi
  1. Robustness of multiple covariate adjustment in logistic regression
  2. Dropout issue for longitudinal analysis
  3. Multiple comparison issue
  4. Theory of martingale in survival analysis
  5. Random effects issue in meta analysis
  6. Investigation for Bayesian/frequentist joint paradigm
  7. Censored data issue in predictive models

 

Pharmaceutical Medicine Course :
Master’s Program, Doctoral Program

This course principally aims to develop researchers and educators with advanced, professional knowledge and abilities in the life science and medicinal science fields, as well as researchers and educators capable of analyzing clinical trial data and creating clinical trial programs, and researchers and educators capable of formulating strategic and global pharmaceutical development plans.

【Major subjects】(advanced studies, seminars, advanced experiments)

  • Special Lecture on Pharmaceutical Medicine(Ⅰ、Ⅱ、Ⅲ)
  • Seminar on Pharmaceutical Medicine(Ⅰ、Ⅱ)
  • Lab.Work on Pharmaceutical Medicine
  • Comprehensive Laboratory on Biostatistics
  • Special Lecture on Pharmaceutical Medicine
  • Seminar on Pharmaceutical Medicine
  • Research Work on Pharmaceutical Medicine
Field of SpecializationResearch Area
Pharmaceutical Medicine
Associate Professor:Mamoru Narukawa
  1. Points to consider in designing a new drug development strategy
  2. Design and implementation of post-marketing safety measures
  3. Improvement of efficiency in the early clinical development
  4. Investigation of the development strategy for anticancer pharmaceuticals
  5. Evaluation of the influence of ethnic factors on the assessment of medicines’ efficacy and safety
  6. Application of Real World Data to new drug development
  7. Evaluation of pharmaceutical regulatory policies and investigation of their effective utilization

 

Division of Pharmacy

Clinical pharmacy course: Doctoral Program

By working on leading-edge research projects in 9 specialized fields and learning the ability to discover and solve problems in the scenes of medicine in addition to the highly advanced specialized knowledge in medical pharmacy or clinical pharmacy, researchers, teachers and so forth capable of leading others in medical settings will be trained.

【Major subjects】(advanced studies, seminars, advanced experiments)

  • Special Lecture on Pathophysiology
  • Seminar on Pathophysiology
  • Research Work on Pathophysiology
  • Special Lecture on Clinical Toxicology
  • Seminar on Clinical Toxicology
  • Research Work on Clinical Toxicology
  • Special Lecture on Community Pharmacy
  • Seminar on Community Pharmacy
  • Research Work on Community Pharmacy
  • Special Lecture on Pharmacokinetics
  • Seminar on Pharmacokinetics
  • Research Work on Pharmacokinetics
  • Special Lecture on Pharmacy Practice and Science Ⅰ
  • Seminar on Pharmacy Practice and Science Ⅰ
  • Research Work on Pharmacy Practice and Science Ⅰ
  • Special Lecture on Pharmacy Practice and Science Ⅱ
  • Seminar on Pharmacy Practice and Science Ⅱ
  • Research Work on Pharmacy Practice and Science Ⅱ
  • Special Lecture on Pharmacy Practice and Science Ⅲ
  • Seminar on Pharmacy Practice and Science Ⅲ
  • Research Work on Pharmacy Practice and Science Ⅲ
  • Special Lecture on Pharmacy Practice and Science Ⅳ
  • Seminar on Pharmacy Practice and Science Ⅳ
  • Research Work on Pharmacy Practice and Science Ⅳ
  • Special Lecture on Medical Psychology
  • Seminar on Medical Psychology
  • Research Work on Medical Psychology
Field of SpecializationResearch Area
Pharmacy Practice and ScienceⅠ
Professor:Kouichiro Atsuda
Our laboratory currently conducts four specific research projects focused on proper use of drugs;
  1. PK/PD studies for palliative care drugs
  2. The safe and effective use of anticancer agents, antibiotics and benzodiazepines
  3. Supportive care in patients receiving chemotherapy
  4. Proper administration of drugs administered through feeding tubes
Pharmacy Practice and ScienceⅡ 
Pharmacy Practice and ScienceⅢ
Associate Professor:Hajime Matsubara
  1. Research on an impact of improving diabetes patient outcomes by pharmacists
  2. Research on appropriate use of diabetes drugs
  3. Research on pharmacists' role in nosocomial infection control
  4. Study on susceptibility testing of anticancer drug
  5. Study on the appropriate drug use for headache
  6. Research of an effective activity to avoid risks of doping problems in sports
  7. Study on the appropriate use of anesthetics
  8. Research on individual dosing designs of warfarin
Pharmacy Practice and ScienceⅣ
Professor:Katsuya Otori
 
Clinical Pharmacokinetics
Associate Professor:Masahiro Kobayashi
 
Clinical Toxicology 
Community Pharmacy
Professor:Yuji Yoshiyama
  1. Pharmaceutical care focused on the relationship between hospitals and community pharmacies
  2. Effects of autonomic nervous system activity on chronic heart failure
  3. The role of pharmacists on the home care services
  4. Medication therapy management in community pharmacy practices
  5. Self-medication services in community pharmacy practices
Bioregulatory Medicine
Associate Professor:Yukio Suzuki
Our goal is to understand the cellular regulatory mechanisms of signal transduction pathway in human body.
  1. To analyze the regulatory mechanism of signal transduction in oxidative stress
  2. To clarify the anti-oxidant effect of edaravone
  3. To study the pathogenesis of endotoxin-induced shock lung
  4. To assess the roles of MMP-12 and ADAMDEC-1 in diffuse lung diseases
Medical Psychology
Associate Professor:Etsuko Arita
Department of Medical Psychology practices the researches to understand psychological characteristics of patients in order to build the good relationship between healthcare professionals and patients. We do research on
  1. Characteristics of communications between healthcare professionals and patients
  2. Relationships between psychological characteristics of patients and attitudes for medical treatment
  3. Decision making process for individual medical treatment (including clinical trial)
  4. Educational methods of healthcare professionals