Uehara, S., Saito, K., Asami, H., & Ohta Y. Role of ARHGAP24 in ADP ribosylation factor 6 (ARF6)-dependent pseudopod formation in human breast carcinoma cells. Anticancer Res. 2017; 37: 4837-4844.


Hara, A., Hashimura, M., Tsutsumi, K, Akiya, M., Inukai, M., Ohta, Y., & Saegusa, M. The role of FilGAP, a Rac-specific Rho GTPase-activating protein, in tumor progression and behavior of astrocytomas.Cancer Med. 2016; 5: 3412-3425


Iida, T., Saito, K., Katagiri, K., Kinashi, T., & Ohta Y. The RacGAP protein FilGAP is a negative regulator of chemokine-promoted lymphocyte migration. FEBS Lett. 2016 Apr 30. doi: 10.1002/1873-3468.12189.


Yamada, H., Tsutsumi, K., Nakazawa, Y., Shibagaki, Y., Hattori, S., & Ohta, Y. Src Family Tyrosine Kinase Signaling Regulates FilGAP through Association with RBM10. PLOS ONE 2016; 10.1371/journal.pone.0146593


Tsurumi, H., Kurihara, H., Miura, K., Tanego, A., Ohta, Y., Igarashi, T., Oka, A., Horita, S., Hattori, M., Harita, Y. Afadin is localized at cell-cell contact sites in mesangial cells and regulates migratory polarity. Lab Invest. 2016; 96: 49-59


Morishita, Y., Tsutsumi, K., & Ohta, Y. Phosphorylation of Serine 402 Regulates RacGAP Activity of FilGAP. J. Biol. Chem. 2015; 290:26328-26338


Nakahara, S., Tsutsumi, K., Zuinen, Y., & Ohta, Y. FilGAP, a Rho/ROCK-regulated GAP for Rac controls adherens junctions in MDCK cells. J. Cell Sci. 2015; 128: 2047-2056


Saito, K., Shiino, T., Kurihara, H., Harita, Y., Hattori, S., & Ohta, Y. Afadin regulates RhoA/Rho-associated protein kinase signaling to control formation of actin stress fibers in kidney podocytes. Cytoskeleton (Hoboken). 2015; 72: 146-156


Nishi, T., Takahashi, H., Hashimura, M., Yoshida, T., Ohta, Y., & Saegusa, M. FilGAP, a Rac-specific Rho GTPase-activating protein, is a novel prognostic factor for follicular lymphoma.Cancer Med. 2015; 4: 808-818


Mori, M., Saito, K., & Ohta, Y. ARHGAP22 localizes at endosomes and regulates actin cytoskeleton. PLoS ONE 2014; 9 (6): e100271


Ito, Y., Asada, A., Kobayashi, H., Takano, T., Sharma, G., Saito, T., Ohta, Y., Amano, M., Kaibuchi, K., & Hisanaga, S. Preferential targeting of p39-activated Cdk5 to Rac1-induced lamellipodia. Mol. Cell. Neurosci. 2014; 61: 34-45


Kawaguchi, K., Saito, K., Asami, H., & Ohta, Y. Arf6 acts through FilGAP to down-regulate Rac and regulates plasma membrane blebbing. J. Biol. Chem. 2014; 289: 9675-9682


Saito, K., Ozawa, Y., Hibino, Y., & Ohta, Y. FilGAP, a Rho/Rho-associated protein kinase-regulated GTPase-activating protein for Rac, controls tumor cell migration. Mol. Biol. Cell 2012; 23: 4739-4750


Nieves, B., Jones, CW., Ward, R., Ohta, Y., Reverte, CG., LaFlamme, SE. The NPIY motif in the integrin b1 tail dictates the requirement for talin-1 outside-in signaling. J. Cell Sci. 2010; 123: 1216-1226


Nakagawa, K., Sugahara, M., Yamasaki, T., Kajiho, H., Takahashi, S., Hirayama, J., Minami, Y., Ohta, Y., Watanabe, T., Hata, Y., Katada, T., Nishina, H. Filamin associates with stress signaling kinases MKK7 and MKK4 and regulates JNK activation. Biochem. J. 2010; 427: 237-245


Shifrin, Y., Arora, PD., Ohta, Y., Calderwood, DA., & McCulloch, CA. The role of FilGAP-filamin A interactions in mechanoprotection. Mol. Biol. Cell 2009; 20: 1269-1279


Nishita, M., Yoo, SK., Nomachi, A., Kani, S., Sougawa, N., Ohta, Y., Takada, S., Kikuchi, A., & Minami, Y. Filopodia formation mediated by receptor tyrosine kinase Ror2 is required for Wnt5a-induced cell migration.  J. Cell Biol. 2006; 175: 555-562


Ohta, Y., Hartwig, JH. & Stossel, TP. FilGAP, a GTPase Activating Protein for Rac Binds Filamin A to Control Polar Actin Remodeling.  Nature Cell Biol. 2006; 8: 803-814


Vidali, L., Chen, F., Cicchetti, G., Ohta, Y., & Kwiatkowski, D. Rac1 null mouse embryonic fibroblasts are motile and respond to PDGF. Mol. Biol. Cell 2006; 17: 2377-2390


Yoshida, N., Ogata, T., Tanabe, K., Li, S., Nakazato, M., Kohu, K., Takafuta, T., Shapiro, S., Ohta, Y., Satake, M., & Watanabe, T. Filamin A-bound REBP2bCBFb is retained in the cytoplasm and prevented from functionaing as a partners of the Runx1 transcription factor. Mol. Cell. Biol. 2005; 25: 1003-1012


Woo, MS., Ohta, Y., Rabinovitz, I., Stossel, TP., & Blenis, J. Ribosomal S6 kinase (RSK) regulates phosphorylation of filamin A on an important regulatory site. Mol. Cell. Biol. 2004; 24: 3025-3035


Ueda, K., Ohta, Y., and Hosoya, H. The carboxy-terminal plecstrin homology domain of ROCK interacts with filamin-A. Biochem. Biophys. Res. Commun. 2003; 301: 886-890


Nakamura, T., Komiya, M., Sone, K., Hirose, E., Gotoh, N., Morii, H., Ohta, Y., & Mori, N. Grit, a GTPase-activating protein for the Rho family, regulates neurite extension through association with the TrkA receptor and N-Shc and CrkL/Crk adaptor molecules. Mol. Cell. Biol. 2002; 22: 8721-8734


Vadlamudi, RK., Li, F., Adam, D., Ohta, Y., Stossel, T.P., Kumar, R. Filamin is essential in actin cytoskeleyal assembly mediated by p21-activated kinase 1.  Nature Cell Biol. 2002; 4: 681-690


Sugihara, K, Asano, S, Tanaka, K, Iwamatsu, A, Okawa, K, Ohta, Y. The exocyst complex binds the small GTPase RalA to mediate filopodia formation. Nature Cell Biol. 2002; 4: 73-78


Sasaki, A, Masuda, Y, Ohta, Y, Ikeda, K, Watanabe, K. Filamin associates with Smads and regulates TGF-b signaling. J. Biol. Chem. 2001; 276: 17871-17877


Bellinger, J-M, Astier, C, Sardet, C, Ohta, Y, Stossel, TP, Debant, A.  The Rac1- and RhoG-specific GEF domain of Trio targets filamin to remodel cytoskeletal actin.  Nature Cell Biol. 2000; 2: 888-892.


Ohta, Y, Suzuki, N, Nakamura, S, Hartwig, JH, Stossel, TP. The small GTPase Ra1A targets filamin to induce filopodia. Proc Nat Acad Sci USA 1999; 96: 2122-2128.


Marti A, Luo Z, Cunningham CC, Ohta Y, Hartwig JH, Stossel TP, Kyriakis JM, Avruch J.  Actin-binding protein –280 binds the stress-activated protein kinase (SAPK) activator SEK-1 and is required for tumor necrosis factor- activation of SAPK in melanoma cells.  J Biol Chem. 1997; 272: 2620-2628.


Ohta Y, Hartwig JH.  Phosphorylation of actin-binding protein 280 growth factors is mediated by p90 ribosomal protein S6 kinase.  J Biol Chem. 1996; 271: 11858-11864.


Ohta Y, Hartwig JH.  Actin filament cross-linking by chicken gizzard filamin is regulated  by phosphorylation in vitro.  Biochemistry 1995; 34: 6745-6754.


Ohta Y, Stossel TP, Hartwig JH.  Ligand-sensitive binding of the high-affinity IgG receptor (FcgR1) to actin-binding protein.  Cell.  1991; 67: 275-282.